Ketamine’s been around for a while now, and it’s become a handy tool for doctors. It can put you to sleep during surgery, help with tough pain, and even shows promise for treating depression. But here’s the thing – ketamine can also raise your blood pressure. So, it is important to understand what’s going on to make sure everything stays safe.

What Does Ketamine Do to Your Body’s Communication System?

Your body acts as a vast network of communication channels, and ketamine disrupts this network by interacting with specific receptors in the brain and spinal cord.

These receptors, called NDMA receptors, play an important role in regulating pain perception and other bodily functions. When ketamine binds to these receptors, it basically disrupts the system.

This disruption has a domino effect. One consequence is the activation of the sympathetic nervous system, also known as the “fight-or-flight” response. When activated, this system prepares your body for action, increasing your heart rate, blood pressure, and alertness.

Does Ketamine Cause Temporary Changes in Blood Pressure?

Ketamine’s effect on blood pressure is usually temporary. Studies show it might cause a small or moderate increase in your blood pressure and heart rate right after you get it. But this usually only lasts for a few minutes or hours, depending on the amount of ketamine given and how your body reacts.

Why Ketamine Affects Us Differently?

Factors like age, weight, and any health problems you already have can play a significant role in how ketamine affects your blood pressure. For example, people with hypertension (high blood pressure) may experience more rise compared to those with normal blood pressure.

This is why it is super important to keep an eye on your blood pressure during and after ketamine use. Your healthcare providers will check it regularly to make sure it stays in a safe range for you.

How Can We Manage and Control the Rise in Blood Pressure?

There are several strategies that can help manage blood pressure during ketamine use. These often involve:

  • Monitoring: Regular blood pressure and heart rate checks are essential to identify any potential issues.
  • Pre-existing conditions: If you have a pre-existing medical condition that affects blood pressure, it is important to inform your healthcare provider beforehand. They may adjust the ketamine dose or recommend additional medications to manage blood pressure.
  • Open communication: Discussing any concerns or discomfort related to blood pressure changes with your healthcare provider is important.


Ketamine is a valuable drug in many medical settings. While it can temporarily raise blood pressure, understanding this effect and using proper management strategies helps healthcare providers use ketamine safely and effectively.

*Remember: Open communication with your doctor is key to a safe and successful ketamine experience. If you have any questions about ketamine treatment, feel free to consult our experts at Balanced Ketamine. Contact us today at (913) 871-9888.

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